Institute for Frontier Life and Medical Sciences, Kyoto University

Identification of a viral factor that impairs immune responses in COVID-19 patients

A research group led by Prof. Koyanagi and Associate Professor Kei Sato from The Institute of Medical Science, The University of Tokyo (IMSUT) aimed to characterize the viral factor(s) determining immune activation upon SARS-CoV-2 infection and found that ORF3b, a gene encoded by SARS-CoV-2, is a potent IFN antagonist.

The results of this research were published in “Cell Reports” on September 4, 2020.

For details, please visit IMSUT’s website.