{"id":6021,"date":"2025-03-26T10:49:55","date_gmt":"2025-03-26T01:49:55","guid":{"rendered":"https:\/\/www.infront.kyoto-u.ac.jp\/?page_id=6021"},"modified":"2025-03-31T11:03:38","modified_gmt":"2025-03-31T02:03:38","slug":"labo02","status":"publish","type":"page","link":"https:\/\/www.infront.kyoto-u.ac.jp\/en\/laboratory\/labo02\/","title":{"rendered":"LAB. OF MEDICAL VIROLOGY"},"content":{"rendered":"<div id=\"pagehead\">\n<h2>LABORATORY<span>About our laboratory<\/span><\/h2>\n<\/div>\n<div id=\"pankuzu\"><a href=\"..\/..\/\">HOME<\/a> &gt; <a href=\"..\/\">Faculty<\/a> &gt; LAB. OF MEDICAL VIROLOGY<\/div>\n<p><main id=\"main\" class=\"laboratory\"><\/p>\n<div class=\"contents\">\n<div class=\"department\">\n<p class=\"field\"><span>DEPARTMENT OF VIRUS RESEARCH<\/span>LAB. OF MEDICAL VIROLOGY<\/p>\n<\/p><\/div>\n<ul class=\"web-list\">\n<li><a href=\"https:\/\/medvirology.infront.kyoto-u.ac.jp\/\" target=\"_blank\" rel=\"noopener\"><img decoding=\"async\" src=\"\/assets\/img\/laboratory\/i_web.svg\" alt=\"Website\"><\/a><\/li>\n<li><a href=\"https:\/\/twitter.com\/HashiguchiLab\" target=\"_blank\" rel=\"noopener\"><img decoding=\"async\" src=\"\/assets\/img\/laboratory\/i_x.svg\" alt=\"Twitter\"><\/a><\/li>\n<\/ul><\/div>\n<div class=\"message\">\n<h3 class=\"tit\"> MESSAGE FROM THE LAB <\/h3>\n<div class=\"contents\">\n<p>Our laboratory has been studying therapeutics for viral diseases, structures of virus-host interactions, and viral pathogenesis. If you are interested in structure-based viral research, please contact our laboratory.<\/p>\n<\/p><\/div>\n<\/p><\/div>\n<div class=\"photo\"><img decoding=\"async\" src=\"\/assets\/img\/laboratory\/labo02\/photo2025.jpg\" alt=\"LAB. OF MEDICAL VIROLOGY\"><\/div>\n<div class=\"member\">\n<div class=\"contents\">\n<div class=\"professer\">\n<div class=\"photo-p\"><img decoding=\"async\" src=\"\/assets\/img\/laboratory\/labo02\/prof.jpg\"><\/div>\n<div class=\"identity\">\n<p><span class=\"position\">Professor<\/span><span class=\"name\">Takao Hashiguchi<\/span><\/p>\n<\/div>\n<ul class=\"msg-list\">\n<li><a href=\"https:\/\/medvirology.infront.kyoto-u.ac.jp\/\" target=\"_blank\" rel=\"noopener\"><img decoding=\"async\" src=\"\/assets\/img\/laboratory\/i_web.svg\" alt=\"Website\"><\/a><\/li>\n<li><a href=\"m&#97;&#105;&#108;&#116;&#111;&#58;&#116;&#97;&#107;&#97;&#111;&#104;&#64;&#105;&#110;&#102;&#114;&#111;&#110;&#116;&#46;&#107;&#121;&#111;&#116;&#111;&#45;&#117;&#46;&#97;&#99;&#46;jp\"><img decoding=\"async\" src=\"\/assets\/img\/laboratory\/i_ms.svg\" alt=\"Mail\"><\/a><\/li>\n<\/ul><\/div>\n<div class=\"assistant\">\n<div>\n<p><span class=\"position\">Assistant Professor<\/span><br \/><span class=\"name\">Tateki Suzuki<\/span><\/p>\n<p><a href=\"m&#97;&#105;&#108;&#116;&#111;&#58;&#115;&#117;&#122;&#117;&#107;&#105;&#46;&#116;&#97;&#116;&#101;&#107;&#105;&#46;&#55;&#121;&#64;&#107;&#121;&#111;&#116;&#111;&#45;&#117;&#46;&#97;&#99;&#46;jp\"><img decoding=\"async\" src=\"\/assets\/img\/laboratory\/i_ms.svg\" alt=\"Mail\"><\/a><\/p>\n<\/p><\/div>\n<div>\n<p><span class=\"position\">Assistant Professor<\/span><br \/><span class=\"name\">Yuma sato<\/span><\/p>\n<p><a href=\"&#109;&#97;&#105;&#108;&#116;&#111;&#58;&#115;&#97;&#116;&#111;&#46;&#121;&#117;&#109;&#97;&#46;&#51;&#117;&#64;&#107;&#121;&#111;&#116;&#111;&#45;&#117;&#46;&#97;&#99;&#46;&#106;&#112;\"><img decoding=\"async\" src=\"\/assets\/img\/laboratory\/i_ms.svg\" alt=\"Mail\"><\/a><\/p>\n<\/p><\/div>\n<div>\n<p><span class=\"position\">Assistant Professor<\/span><br \/><span class=\"name\">Kanako Kimura<\/span><\/p>\n<p><a href=\"m&#97;&#105;&#108;&#116;&#111;&#58;&#107;&#105;m&#117;&#114;&#97;&#46;&#107;&#97;&#110;&#97;&#107;&#111;&#46;&#55;&#99;&#64;&#107;&#121;&#111;&#116;&#111;&#45;&#117;&#46;&#97;&#99;&#46;jp\"><img decoding=\"async\" src=\"\/assets\/img\/laboratory\/i_ms.svg\" alt=\"Mail\"><\/a><\/p>\n<\/p><\/div>\n<\/p><\/div>\n<div class=\"staff\">\n<p class=\"position\">Member<\/p>\n<p class=\"staff\">Secretary\uff1a<span class=\"name\">Yoko Enjo<\/span><\/p>\n<p class=\"staff\">Graduate Students\uff1a<span class=\"name\">Jie Sasaki<\/span><\/p>\n<p class=\"staff\">Graduate Students\uff1a<span class=\"name\">Hisano Yajima<\/span><\/p>\n<p class=\"staff\">Technical Assistant\uff1a<span class=\"name\">Yukari Nakajima<\/span><\/p>\n<\/p><\/div>\n<\/p><\/div>\n<\/p><\/div>\n<div class=\"research\">\n<h3 class=\"tit\">RESEARCH<\/h3>\n<div class=\"contents\">\n<div class=\"field\">\n<h4><span>Elucidation of viral pathogenesis and development of prevention and therapeutics for viral infections <\/span><\/h4>\n<p>Infectious diseases still have been a fatal threat to children, worldwide. To solve the problem, we have been studying on pediatric virology. In particular, we focus on the mechanisms of viral entry into cells and the inhibition of entry by compounds, peptides, glycans, and antibodies, using a combination of virological and structural biological approaches. Our major goals are the elucidation of viral pathogenesis and the development of preventive and therapeutic methods for viral diseases.<\/p>\n<\/p><\/div>\n<\/p><\/div>\n<div class=\"bg-field\">\n<div class=\"field\">\n<h4><span>Structures of viral glycoproteins and a picture of virus-infected cells<\/span><\/h4>\n<div class=\"with-photo\">\n<p class=\"txt\">Our laboratory focuses on pediatric viral diseases. Combining molecular biology, biochemistry, physical chemistry, virology, and structural biology techniques, we have been studying the mechanisms by which viral infections cause pathogenesis and the mechanisms by which the human immune system counteracts viral infections. As for structural analysis, we mainly utilize X-ray crystallography and cryo-electron microscopy to visualize the interactions between host factors\/therapeutic molecules and viral proteins.<\/p>\n<p class=\"img\"><img decoding=\"async\" src=\"\/assets\/img\/laboratory\/labo02\/img01.jpg\" alt=\"Structures of viral glycoproteins and a picture of virus-infected cells\"><\/p>\n<\/p><\/div>\n<\/p><\/div>\n<div class=\"field\">\n<h4><span>Complex Structures of virus glycoproteins bound to inhibitory molecules and a picture of virus-infected brain organoids.<\/span><\/h4>\n<div class=\"with-photo\">\n<p class=\"txt\">Building on the above results, we also have been studying basic research for vaccine development based on protein structures, and developing therapeutic antibodies, compounds, and peptides. In particular, we have been focusing on designing vaccine antigens and developing novel methods for antibody production.<\/p>\n<p class=\"img\"><img decoding=\"async\" src=\"\/assets\/img\/laboratory\/labo02\/img02.jpg\" alt=\"Complex Structures of virus glycoproteins bound to inhibitory molecules and a picture of virus-infected brain organoids.\"><\/p>\n<\/p><\/div>\n<\/p><\/div>\n<\/p><\/div>\n<\/p><\/div>\n<p>  \n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n<br \/>\n<\/main><\/p>\n","protected":false},"excerpt":{"rendered":"<p>LABORATORYAbout our laboratory HOME &gt; Faculty &gt; LAB. OF MEDICAL VIROLOGY DEPARTMENT OF VIRUS RESEARCHLAB. OF MEDICAL VIROLOGY MESSAGE FROM THE LAB Our laboratory has been studying therapeutics for viral diseases, structures of virus-host interactions, and viral pathogenesis. If you are interested in structure-based viral research, please contact our laboratory. ProfessorTakao Hashiguchi Assistant ProfessorTateki Suzuki [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":131,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_locale":"en_US","_original_post":"https:\/\/www.infront.kyoto-u.ac.jp\/?page_id=6019","footnotes":""},"class_list":["post-6021","page","type-page","status-publish","hentry","en-US"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.infront.kyoto-u.ac.jp\/wp-json\/wp\/v2\/pages\/6021","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.infront.kyoto-u.ac.jp\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.infront.kyoto-u.ac.jp\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.infront.kyoto-u.ac.jp\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.infront.kyoto-u.ac.jp\/wp-json\/wp\/v2\/comments?post=6021"}],"version-history":[{"count":2,"href":"https:\/\/www.infront.kyoto-u.ac.jp\/wp-json\/wp\/v2\/pages\/6021\/revisions"}],"predecessor-version":[{"id":6170,"href":"https:\/\/www.infront.kyoto-u.ac.jp\/wp-json\/wp\/v2\/pages\/6021\/revisions\/6170"}],"up":[{"embeddable":true,"href":"https:\/\/www.infront.kyoto-u.ac.jp\/wp-json\/wp\/v2\/pages\/131"}],"wp:attachment":[{"href":"https:\/\/www.infront.kyoto-u.ac.jp\/wp-json\/wp\/v2\/media?parent=6021"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}