{"id":6557,"date":"2025-05-30T09:47:20","date_gmt":"2025-05-30T00:47:20","guid":{"rendered":"https:\/\/www.infront.kyoto-u.ac.jp\/?p=6557"},"modified":"2025-05-30T10:02:45","modified_gmt":"2025-05-30T01:02:45","slug":"post-6548","status":"publish","type":"post","link":"https:\/\/www.infront.kyoto-u.ac.jp\/en\/post-6548\/","title":{"rendered":"Analysis of Borna disease virus infection defense mechanisms using endogenous bornavirus-like element (EBLN) knockout mice \u2014 elucidating the antiviral activities of EBLN-derived piRNAs and the IFN-\u03b3\/TLR7 pathway"},"content":{"rendered":"<p>Rie Koide1, Takaya Abe2, Taichi Harimoto1, Anselmo Jiro Kamada3, Yuka Saito1, Matteo Guerrini\uff11, Asami Fujii1, Erica Parrish1, Masayuki Horie4, Hiroshi Kiyonar2, Kazuhiko Yamamoto4, Keizo Tomonaga5, Nicholas F Parrish1<br \/>\n(\uff11\uff0e\u7406\u5316\u5b66\u7814\u7a76\u6240 \u7d71\u5408\u751f\u547d\u533b\u79d1\u5b66\u7814\u7a76\u30bb\u30f3\u30bf\u30fc\u3001\uff12\uff0e\u7406\u5316\u5b66\u7814\u7a76\u6240 \u751f\u547d\u533b\u79d1\u5b66\u7814\u7a76\u30bb\u30f3\u30bf\u30fc\u3001\uff13\uff0e\u30aa\u30c3\u30af\u30b9\u30d5\u30a9\u30fc\u30c9\u5927\u5b66\u3001\uff14\uff0e\u5927\u962a\u516c\u7acb\u5927\u5b66 \u5927\u5b66\u9662\u7363\u533b\u5b66\u7814\u7a76\u79d1\u3001\uff15\uff0e\u4eac\u90fd\u5927\u5b66 \u533b\u751f\u7269\u5b66\u7814\u7a76\u6240)<\/p>\n<p><strong>Interferon and TLR genes, but not endogenous bornavirus-like elements, limit BoDV1 replication after intracerebral infection<\/strong><\/p>\n<p>PLoS Pathogens. (2025) \u3000doi: 10.1371\/journal.ppat.1013165<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Rie Koide1, Takaya Abe2, Taichi Harimoto1, Anselmo Jiro Kamada3, Yuka Saito1, Matteo Guerrini\uff11, Asami Fujii1, Erica Parrish1, Masayuki Horie4, Hiroshi Kiyonar2, Kazuhiko Yamamoto4, Keizo Tomonaga5, Nicholas F Parrish1 (\uff11\uff0e\u7406\u5316\u5b66\u7814\u7a76\u6240 \u7d71\u5408\u751f\u547d\u533b\u79d1\u5b66\u7814\u7a76\u30bb\u30f3\u30bf\u30fc\u3001\uff12\uff0e\u7406\u5316\u5b66\u7814\u7a76\u6240 \u751f\u547d\u533b\u79d1\u5b66\u7814\u7a76\u30bb\u30f3\u30bf\u30fc\u3001\uff13\uff0e\u30aa\u30c3\u30af\u30b9\u30d5\u30a9\u30fc\u30c9\u5927\u5b66\u3001\uff14\uff0e\u5927\u962a\u516c\u7acb\u5927\u5b66 \u5927\u5b66\u9662\u7363\u533b\u5b66\u7814\u7a76\u79d1\u3001\uff15\uff0e\u4eac\u90fd\u5927\u5b66 \u533b\u751f\u7269\u5b66\u7814\u7a76\u6240) Interferon and TLR genes, but not endogenous bornavirus-like elements, limit BoDV1 replication after intracerebral infection PLoS Pathogens. (2025) \u3000doi: 10.1371\/journal.ppat.1013165<\/p>\n","protected":false},"author":3,"featured_media":6560,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_locale":"en_US","_original_post":"https:\/\/www.infront.kyoto-u.ac.jp\/?p=6548","footnotes":""},"categories":[1],"tags":[],"labo":[],"labo_en":[47],"class_list":["post-6557","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-achievements","labo_en-labo03","en-US"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.infront.kyoto-u.ac.jp\/wp-json\/wp\/v2\/posts\/6557","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.infront.kyoto-u.ac.jp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.infront.kyoto-u.ac.jp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.infront.kyoto-u.ac.jp\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.infront.kyoto-u.ac.jp\/wp-json\/wp\/v2\/comments?post=6557"}],"version-history":[{"count":1,"href":"https:\/\/www.infront.kyoto-u.ac.jp\/wp-json\/wp\/v2\/posts\/6557\/revisions"}],"predecessor-version":[{"id":6558,"href":"https:\/\/www.infront.kyoto-u.ac.jp\/wp-json\/wp\/v2\/posts\/6557\/revisions\/6558"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.infront.kyoto-u.ac.jp\/wp-json\/wp\/v2\/media\/6560"}],"wp:attachment":[{"href":"https:\/\/www.infront.kyoto-u.ac.jp\/wp-json\/wp\/v2\/media?parent=6557"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.infront.kyoto-u.ac.jp\/wp-json\/wp\/v2\/categories?post=6557"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.infront.kyoto-u.ac.jp\/wp-json\/wp\/v2\/tags?post=6557"},{"taxonomy":"labo","embeddable":true,"href":"https:\/\/www.infront.kyoto-u.ac.jp\/wp-json\/wp\/v2\/labo?post=6557"},{"taxonomy":"labo_en","embeddable":true,"href":"https:\/\/www.infront.kyoto-u.ac.jp\/wp-json\/wp\/v2\/labo_en?post=6557"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}