Diverse stresses including infection with viruses and bacteria cause inflammation by activating innate immunity. In addition, inflammation is revealed to be involved in various diseases such as autoimmunity, cancer and metabolic syndrome. We are aiming to uncover the molecular mechanisms of inflammation and its regulation in the innate immune system by using genetically modified animals. Our current focus is on the post-transcriptional control of inflammatory genes by uncovering the roles of mRNA degradation in immune regulation.
- Graduate School of Pharmaceutical Sciences
- Graduate School of Medicine
- Graduate School of Biostudies