Institute for Frontier Life and Medical Sciences, Kyoto University

Department of Biosystems Science

Lab. of Tissue Homeostasis


Professor Fumiko Toyoshima (ftoyoshi∗
Assistant Professor Yukako Oda (ykoda∗
Assistant Professor Riki Ishibashi(rishibas∗
Assistant Professor Ryo Ichijyo(richijo∗

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Research theme

Stem cells in adult tissues exist in a quiescent state. When they are needed in tissue homeostasis or repair, they exit a quiescent state and undergo symmetric/asymmetric cell division to give rise to differentiation-committed progenitor cells. Our group seeks to explore the molecular mechanisms underlying oriented stem cell division, stem cell activation, and cell fate determination. We also want to know how stem cells adopt to physiological changes in the body.

1) Epidermal stem cell proliferation and differentiation in skin homeostasis.
2) Cell fate determination of lymphoid cells via symmetric/asymmetric cell division.
3) Tissue stem cell activation during pregnancy.


Graduate Education

  • Graduate School of Biostudies


  • Doctor course 5, Master course 3.

Contact Information

Person to Contact Professor Fumiko Toyoshima
TEL 075-751-4015
E-mail ftoyoshi∗

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