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DEPARTMENT OF VIRUS RESEARCHLAB. OF Viral Molecular Pathogenesis

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MESSAGE FROM THE LAB

We study DNA viruses and seek to bridge molecular mechanisms with organismal biology to advance our understanding and control of viral infectious diseases. However, our ultimate interest extends beyond the viruses themselves. Through investigating virus–host interactions, we aim to uncover fundamental principles of life science.Training the next generation of life scientists is also an important mission of our laboratory. We welcome students who are eager to explore the mysteries of life and pursue new discoveries. No prior background in virology or biology is required. If you are interested in our research, please feel free to contact us.

ProfessorAkihisa Kato

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RESEARCH

Laboratory of Viral Molecular Pathogenesis

We study large DNA viruses, including herpes simplex virus and cytomegalovirus, to better understand both infectious diseases and fundamental biological processes. Viruses are not only pathogens but also a “mirror of life” that reflects hidden biological rules awaiting discovery. By elucidating the molecular interplay between viruses and their hosts, we seek to uncover fundamental principles of life that have yet to appear in textbooks and to translate these discoveries into novel therapeutic strategies.

Our research is guided by a simple idea: understanding viruses helps us understand life. One of our goals is to uncover how DNA viruses, such as herpesviruses, exploit cellular machinery, evade immune defenses, and persist within their hosts. Insights from these studies may contribute to the development of new antiviral strategies. At the same time, we use viruses as powerful tools for discovery. By studying how viruses interact with cells, we seek to identify previously unknown genes, cellular functions, and even fundamental biological principles that remain hidden from current textbooks. We believe that virology not only advances our understanding of infectious diseases but also provides a unique window into the fundamental mechanisms of life.