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Dec 2, 2019
Symmetry Breaking of Biological Cells
Date: Dec. 2,(Mon.)2019 13:30~15:00
Room: Seminar Room104, 1st Floor, Bldg. #2 of Institute for Frontier Life and Medical Sciences, Kyoto University
Speaker: Prof. Frank Jülicher
Max Planck Institut
für Physik komplexer Systeme
Dresden, Germany
Title: Symmetry Breaking of Biological Cells

Abstract

Living matter is highly dynamic and organizes in complex patterns and spatial structures. A fundamental question in biology is to understand how cells break symmetries. Examples for cell symmetry breaking are cell polarity and cell chirality, which play an important role during the formation of complex organisms. Cell symmetry breaking is often mediated by active dynamical processes. The prototype of such active processes is force generation by motor molecules. Molecular motors are driven by the chemical energy of a fuel. They generate movements and forces on molecular scales. Active force generation gives rise to unconventional mechanical behaviors and spontaneous movements of the gel-like materials inside the cell. I will discuss the basic physics of the generation of flow patterns  in the cell cortex ba active cellular processes. I will show that such flows provide a key mechanism for cellular symmetry breaking that can play a role for the establishment of the main body axes as well as the left-right asymmetry of developing organisms.
(Language: English)

 

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