LiMe 京都大学医生物学研究所

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2025年4月11日
【13th nanobiofluids seminar】Unconventional Nano-Biophotonic Tools For Imaging and Sensing Applications
日時: 2025年4月11日(金)10:30~11:30
場所: 医生物学研究所 2号館1階セミナー室(104室)
Seminar Room (Room 104), 1st Floor, Bldg. No.2
演者: Aniruddha Ray, Ph.D. Associate Professor
Department of Physics and Astronomy, University of Toledo, Ohio.
演題: Unconventional Nano-Biophotonic Tools For Imaging and Sensing Applications

講演要旨

Our research focuses on developing innovative imaging and biosensing platforms that integrate nanotechnology and photonics for a wide range of biomedical applications, from oncology to infectious disease detection. Here I will delve into two distinct types of platforms.
First, I will introduce lens-free on-chip microscopy, a powerful alternative to traditional optical microscopy, that addresses key limitations associated with objective lenses, such as limited field of view. Using computational techniques based on holography and fluorescence, these on-chip microscopy systems enable wide-area imaging and high-throughput analysis, while offering a cost-effective (~$100) and portable solution. I will discuss the design of on-chip microscopy and its utility towards a wide range of applications, particularly for screening anti-cancer drugs and detection of pathogens.
In the second part, I will shift focus to the development of ultrabright nanoparticles tailored for high-resolution deep-tissue structural and functional imaging. These nanoparticles consist of an inorganic perovskite nanocrystal core enclosed by multiple polymer shells, which can encapsulate fluorescent sensors and drug molecules. These multi-core-shell nanoparticles are being utilized in tasks like labeling cells and mapping various chemical analytes in cells and tissues for early diagnostics and therapy monitoring.

20250411_Dr.Ray_flyer

Host:
医生物学研究所 ナノ生物工学分野
新宅 博文 Hirofumi Shintaku, shintaku[@]infront.kyoto-u.ac.jp