日時：	2026年3月19日（木）15：00～16：00
場所：	医生研1号館1階会議室（134室） Conference Room (Room 134), 1st Floor, Bldg. No.1
演者：	Anthony, Zannas, MD, MSc, Ph.D. Associate Professor Departments of Psychiatry and Genetics, University of North Carolina at Chapel Hill
演題：	Live fast die young: the role of epigenetics in stress and aging

講演要旨

Psychosocial and other forms of environmental stress – especially when
chronic or excessive – have been repeatedly associated with accelerated aging and
increased disease risk. With rapid aging of the world population, the need to elucidate the
underlying mechanisms is pressing, now more so than ever. Among candidate
mechanisms, this interactive talk will present evidence on the role of epigenetics,
biochemical processes that can be set into motion by stressors and in turn influence
genomic function and complex phenotypes, including aging-related outcomes. The talk
will first provide a background and rationale for examining the role of epigenetics in
stress and aging. It will then synthesize and contextualize interdisciplinary, published and
unpublished studies from our group and others, spanning three research themes: (i) The
impact of psychosocial stress on epigenetic aging in humans; (ii) Epigenetic interplay
between stress and immune function at the cell-type level; (iii) Insights from modeling
the epigenetic and cell states of chronic stress. The talk will conclude with future
directions, take-home messages, and open discussion with the audience.

AIC Seminar_flyer_Anthony_v2

Host: Eriko Kage-Nakadai, nakadai[@]infront.kyoto-u.ac.jp