【Medical Chemistry Seminar】The power of ONE: Immunoligy in the age of single cell genomics
|Dr. Ido Amit
Weizmann Institute of Science
|The power of ONE: Immunoligy in the age of single cell genomics
The immune system is a complex, dynamic and plastic network composed of various
interacting cell types that are constantly sensing and responding to environmental cues.
From very early on, the immunology field has invested great efforts to characterize the various
immune cell types and elucidate their functions. However, accumulating evidence indicates
that current technologies and classification schemes are limited in their ability
to account for the functional heterogeneity of immune processes. Single cell genomics
hold the potential to revolutionize the way we characterize complex immune cell assemblies and
study their spatial organization, dynamics, clonal distribution, pathways, and crosstalk.
This emerging field can greatly affect basic and translational research of the immune
system. I will discuss how recent single cell genomic studies are changing our perspective of
various immune related pathologies from cancer to autoimmune disease and neurodegeneration.
Finally, I will consider recent and forthcoming technological and analytical advances in
single cell genomics and their huge
potential impact on the future of immunology research and immunotherapy.
Contact: Prof. Osamu Takeuchi
E-mail: otake*mfour.med.kyoto-u.ac.jp （*を@に変えてください。）
Hosted by Department of Medical Chemistry Graduate School of Medicine, Kyoto University