日時：	2023年9月26日（火）13：30～15：00
場所：	Room 501, 5th floor, Bldg. #3 Institute for Life and Medical Sciences, Kyoto University
演者：	Prof. Yoh Iwasa Department of Biology, Kyushu University Fukuoka, Japan
演題：	The genetic structure within a single tree is determined by the behavior of the stem cells in the meristem.

講演要旨

Genomic sequencing revealed that somatic mutations cause a genetic
differentiation of the cells in a single tree. We studied a mathematical model for
stem cell proliferation in the shoot apical meristem (SAM), and evaluated the
phylogenetic distance between cells sampled from different portions of a shoot.
The plant tissue has cell walls that suppress the exchange of location between
cells, leading to the genetic differentiation of cells according to the angle
around the shoot and a larger genetic variance among cells in the body.
Assumptions: stem cells in the SAM normally undergo asymmetric cell division,
producing successor stem cells and differentiated cells. Occasionally, a stem
cell fails to leave its successor stem cell and the vacancy is filled by the
duplication of one of the nearest neighbor stem cells.
Results: the genetic diversity of cells sampled at the same position along the
shoot increases with the distance from the base of the shoot. Stem cells hold a
larger variation if they are replaced only by the nearest neighbors. The
coalescent length between two cells increases not only with the difference in
the position along the shoot but also in the angle around the shoot axis.
Iwasa Y, Tomimoto S, Satake A. 2023. Genetics 223: iyad020  (Language: English)

 

contact: Atsushi Mochizuki
Laboratory of Mathematical Biology,
Institute for Life and Medical Sciences,
Kyoto University
Email: mochi*infront.kyoto-u.ac.jp（*を@へ変えてください。）
Tel: 075-751-4612