日時：	2024年10月25日（金）16：00～17：00
場所：	Seminar Room (Rm 127) 1st floor, Bldg No.1 of LiMe https://www.infront.kyoto-u.ac.jp/en/access/
演者：	Prof. Shin Yoshizawa Tohoku University, SONIRE Therapeutics
演題：	Ultrasound-guided focused ultrasound treatment using cavitation bubble - From elemental technology development to startup establishment -

講演要旨

High-intensity focused ultrasound (HIFU) is a noninvasive treatment modality for tumors.
Ultrasound generated outside a body is focused on the target tissue and the absorption of the HIFU
energy in the focal region induces a temperature increase resulting in the thermal coagulation of the
target tissue. Several HIFU treatment devices have received regulatory approval in Japan, but they
have not become widespread. We have developed a HIFU treatment system with high safety and
efficacy by using cavitation bubbles. Cavitation bubble clouds can be generated by an extremely highintensity
ultrasound pulse. Cavitation bubbles accelerate the ultrasonic tissue heating and also act as
contrast agents in ultrasound imaging for the treatment monitoring. A clinical study using this approach
was conducted in 2017 and a start-up company was established in 2020 with the aim of social
implementation of this technology. The startup is currently conducting clinical trials in Japan for
pancreatic cancer, and is preparing for clinical trials in the United States.

【20241025開催】6th nanobiofluids seminar（Prof. Shin Yoshizawa_Tohoku University）

Host: Hirofumi Shintaku, shintaku[@]infront.kyoto-u.ac.jp