2025年2月14日 【Theoretical Biology Seminar】Genome and Sex Chromosome Analyses of Japanese Frogs Carrying Both XY and ZW Chromosomes Within the Same Species |
日時: | 2025年2月14日(金)15:00~16:30 |
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場所: | Room 501, 5th floor, Bldg. #3 Institute for Life and Medical Sciences, Kyoto University |
演者: | Yukako Katsura (EHUB, Kyoto University) |
演題: | Genome and Sex Chromosome Analyses of Japanese Frogs Carrying Both XY and ZW Chromosomes Within the Same Species |
講演要旨
The evolution of sex chromosomes, particularly sex chromosome turnover,
is a complex and fascinating topic in genetics and evolutionary biology. Sex
chromosome turnover refers to the process in which the sex chromosome system
changes from XY to ZW (or vice versa), or in which sex chromosomes with different
evolutionary origins emerge within the same system (e.g., from one XY system to
another XY system). To study sex chromosome turnover, we focus on the Japanese
frog (Glandirana rugosa), which possesses both XY and ZW sex chromosomes
within the same species, and investigate the molecular mechanisms behind the
turnover in the frog (Review: Hayashi et al. JB 2024). Previously, we sequenced the
nuclear genome of the ZZ frog (Katsura et al. LSA 2021) and identified sex-linked
genes in two populations of the XY and ZW frogs (Miura et al. Mol Ecol 2022). It has
been suggested that sex chromosomes originating from at least three different
chromosomal lineages have independently emerged within this species. The frogs
have a total of 13 chromosomes, and in two populations (Tokai/Eastern Central
Japan and Hokuriku-Tohoku/North-Western Japan), chromosome 7 has
morphologically differentiated into both ZW and XY chromosomes. However, in other
populations, sex chromosomes do not show any morphological differentiation. In this
seminar, I introduce the background of our sex chromosome study and present the
results of sequence comparisons of morphologically differentiated XY and ZW
chromosomes, as well as findings from our analyses of populations, genome, and
transcriptome.
contact: Takashi Okada
Laboratory of Mathematical Biology,
Institute for Life and Medical Sciences, Kyoto University
Email: okada.Takashi.3z[@]infront.kyoto-u.ac.jp