| 2026年10月26日 【28th nanobiofluids seminar】Using organoids and microfluidics to study antagonistic and synergetic cell-cell interactions: cancer-immune interactions and mechanobiology |
| 日時: | 2026年10月26日(月)13:00~14:00 |
|---|---|
| 場所: | 京都大学高等研究院ヒト生物学高等研究拠点(ASHBi)地階会議室 ASHBi Conference Room, B1F, Faculty of Medicine Bldg. B URL:https://ashbi.kyoto-u.ac.jp/access/ |
| 演者: | Charles Baroud, Ph.D. Professor, Ecole Polytechnique and Institut Pasteur |
| 演題: | Using organoids and microfluidics to study antagonistic and synergetic cell-cell interactions: cancer-immune interactions and mechanobiology |
講演要旨
I will show two microfluidic approaches to study cell-cell interactions. In the first approach we use parallel
anchored droplets to submit patient-derived cancer organoids to killing by cytotoxic T cells. By tracking the
cell movements it is possible to identify the distinct role of each T cell population and their respective impact
on the killing dynamics. In the second part I will turn to mechanobiology, by introducing a deformable
microfluidic device that is suitable for manipulating spheroids and organoids. I will show how biophysical and
rheological parameters of 3D micro-tissues can be obtained using mechanical forcing and image analysis.
Flyer_CharlesBaroud_ASHBi-seminar
Host:
Host: Hirofumi Shintaku(LiMe), shintaku[@]infront.kyoto-u.ac.jp
Takafumi Ichikawa (ASHBi), ashbi-event[@]mail2.adm.kyoto-u.ac.jp
